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Faculté de médecine dentaire
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Nanci, Antonio

Ph. D.


T : 514 343-5846
F : 514 343-2233

Adresse géographique

Faculté de médecine dentaire
Pavillon Roger-Gaudry, local : A-212
Université de Montréal
2900, Édouard-Montpetit
Montréal (Québec)  H3T 1J4

Adresse postale

Faculté de médecine dentaire
Université de Montréal
C.P. 6128, succ. Centre-ville
Montréal (Québec)  H3C 3J7


  • Directeur du département de stomatologie
  • Professeur titulaire, département de stomatologie
  • Directeur du Laboratoire de recherche sur les tissus calcifiés et les biomatériaux

Champs d’intérêt

  • La caractérisation des protéines dentaires et osseuses
  • Les effets des drogues et pathologies des tissus calcifiés.
  • L’ultrastructure des tissus calcifiés
  • Les mécanismes de minéralisation
  • La santé parodontale
  • Le recours à la thérapie génique pour le contrôle et la réparation tissulaire
  • Les modifications des surfaces des biomatériaux à l’aide de molécules bioactives
  • Le développement de nouvelles approches chirurgicales pour la livraison des biopolymères
  • La réparation tissulaire à l’aide de la bio-ingénierie


  • 1983 – Post-doctoral fellow with Harold C. Slavkin in Craniofacial Developmental & Molecular Biology, University of Southern California, USA
  • 1982 – Doctor of Philosophy in Anatomy & Cell Biology, McGill Univeristy, Canada
  • 1978 – Master of Science in Pathology, Université de Montréal, Canada
  • 1976 – Bachelor of Science in Anatomy & Cell Biology, Université de Montréal, Canada

Publications sélectionnées

Clair S, Variola F, Kondratenko M, Jedrzejowski P, Nanci A, Rosei F, and Perepichka DF. Self-assembled monolayer of alkanephosphoric acid on nanotextured Ti. J Chem Phys, 2008; 128:144705.1-144705.6.

Richert L, Vetrone F, Yi JH, Zalzal SF, Wuest JD, Rosei F and Nanci A. Surface nanopatterning to control cell growth. Adv Mater, 2008; 20: 1488-1492

Trubiani O, Isgro A, Zini N, Antonucci I, Aiuti F, Di PR, Nanci A, Caputi S, Paganelli R. Functional interleukin-7/interleukin-7Ralpha, and SDF-1alpha/CXCR4 are expressed by human periodontal ligament derived mesenchymal stem cells. J.Cell Physiol 2008; 214:706-713.

Zalzal SF, Smith CE, Nanci A (2008): Ameloblastin and amelogenin share a common secretory pathway and are co-secreted during enamel formation. Matrix Biol, 2008; 27:352-359.

Colnot C, Romero D, Huang S, Rahman J, Currey J, Nanci A, Brunski JB, Helms JA. Molecular analysis of healing at a bone-implant interface. J Dent Res 2007; 86: 862-7.

Dang H, Maris T, Yi JH, Rosei F, Nanci A, Wuest JD. Ensuring homology between 2D and 3D molecular crystals. Langmuir 2007; 23 :11980-11985.

Moffatt P, Smith CE, St Arnaud R, Nanci A. Characterization of Apin, a secreted protein highly expressed in tooth-associated epithelia. J Cell Biochem 2007; 103: 941-956.

Nath KG, Ivasenko O, MacLeod JM, Miwa JA, Wuest JD, Nanci A, Perepichka DF, Rosei F. Crystal engineering in two dimensions: An approach to molecular nanopatterning. J Phys Chem C 2007; 111:16996-17007.

Tambasco De Oliveira P, Zalzal SF, Beloti MM, Rosa AL, Nanci A. Enhancement of in vitro osteogenesis on titanium by chemically produced nanotopography. J Biomed Mater Res A  2007; 80A:554-564.

Variola F, Yi JH, Richert L, Wuest JD, Rosei F, Nanci A. Tailoring the surface properties of Ti6Al4V by controlled chemical oxidation. Biomaterials 2007; 29: 1285-1298.

Wazen RM, Tye CE, Goldberg HA, Hunter GK, Smith CE, Nanci A. In vivo functional analysis of polyglutamic acid domains in recombinant bone sialoprotein. J Histochem Cytochem 2007; 55: 35-42.

Zhou H, Dang H, Nanci A, Rochefort A and Wuest JD. Frustrated 2D molecular crystallization. J Am Chem Soc 2007; 129:13774-13775

Lebel O, Perron ME, Maris T, Zalzal SF, Nanci A, Wuest JD. A new class of selective low-molecular-weight gelators based on salts of diaminotriazinecarboxylic acids. Chem Mater 2006; 18: 3616-26.

Leucht P, Kim JB, Wazen R, Currey JA, Nanci A, Brunski JB, Helms JA. Effect of mechanical stimuli on skeletal regeneration around implants. Bone 2006; 40: 919-30.

Moffatt P, Smith CE, Sooknanan R, St-Arnaud R, Nanci A. Identification of secreted and membrane proteins in the rat incisor enamel organ using a signal-trap screening approach. Eur J Oral Sci 2006; 114 Suppl 1: 139-46.

Moffatt P, Smith CE, St-Arnaud R, Simmons D, Wright JT, Nanci A. Cloning of rat amelotin and localization of the protein to the basal lamina of maturation stage ameloblasts and junctional epithelium. Biochem J 2006; 399: 37-46.

Nath KG, Ivasenko O, Miwa JA, Dang H, Wuest JD, Nanci A, Perepichka DF, Rosei F. Rational modulation of the periodicity in linear hydrogen-bonded assemblies of trimesic acid on surfaces. J Am Chem Soc 2006; 128: 4212-3.

Smith CE, Nanci A, Moffatt P. Evidence by signal peptide trap technology for the expression of carbonic anhydrase 6 in rat incisor enamel organs. Eur J Oral Sci 2006; 114 Suppl 1: 147-53.

Tavares MG, Tambasco De Oliveira P, Nanci A, Hawthorne AC, Rosa AL, Xavier SP. Treatment of a commercial, machined surface titanium implant with H2SO4/H2O2 enhances contact osteogenesis. Clin Oral Impl Res 2006; 18: 452-8.

Wazen RM, Moffatt P, Zalzal SF, Daniel NG, Westerman KA, Nanci A. Local gene transfer to calcified tissue cells using prolonged infusion of a lentiviral vector. Gene Ther 2006; 13: 1595-602.

Yi JH, Bernard C, Variola F, Zalzal SF, Wuest JD, Rosei F, Nanci A. Characterization of a bioactive nanotextured surface created by controlled chemical oxidation of titanium. Surface Science 2006; 600: 4613-21.

Bosshardt DD, Nanci A. Hertwig's epithelial root sheath, enamel matrix proteins, and initiation of cementogenesis in porcine teeth. J Clin Periodontol 2004; 31: 184-92.

Fukumoto S, Kiba T, Hall B, Iehara N, Nakamura T, Longenecker G, Krebsbach PH, Nanci A, Kulkarni AB, Yamada Y. Ameloblastin is a cell adhesion molecule required for maintaining the differentiation state of ameloblasts. J Cell Biol 2004; 167: 973-83.

Laboux O, Dion N, Arana-Chavez VE, Ste-Marie L-G, Nanci A. Microwave irradiation of ethanol-fixed bone improves preservation, reduces processing time and allows both light and electron microscopy on a same sample. J Histochem Cytochem 2004; 52: 1267-75.

Nanci A, Wazen RM, Zalzal S, Fortin M, Goldberg HA, Hunter GK, Ghitescu DL. A tracer study with systemically and locally administered dinitrophenylated osteopontin. J Histochem Cytochem 2004; 52: 1591-600.

Bosshardt DD, Nanci A. Immunocytochemical characterization of ectopic enamel deposits and cementicles in human teeth. Eur J Oral Sci 2003; 111: 51-9.

Gascon-Barré M, Demers C, Mirshahi A, Neron S, Zalzal S, Nanci A. The normal liver harbors the vitamin D nuclear receptor in nonparenchymal and biliary epithilial cells. Hepatology 2003; 37: 1034-42.

Laboux O, Ste-Marie L-G, Glorieux FH, Nanci A. Quantitative immunogold labeling of bone sialoprotein and osteopontin in methylmethacrylate-embedded rat bone. J Histochem Cytochem 2003; 51: 61-7.

Tambasco De Oliveira P, Nanci A. Nanotexturing of titanium-based surfaces upregulates expression of bone sialoprotein and osteopontin by cultured osteogenic cells. Biomaterials 2003; 25: 403-13.

Tambasco De Oliveira P, Zalzal S, Irie K, Nanci A. Early expression of bone matrix proteins in osteogenic cell cultures. J Histochem Cytochem 2003; 51: 633-41.

Shimazu Y, Nanci A, Aoba T. Immunodetection of osteopontin at sites of resorption in the pulp of rat molars. J Histochem Cytochem 2002; 50: 911-21.

Arana-Chavez VE, Nanci A. High-resolution immunocytochemistry of noncollagenous matrix proteins in rat mandibles processed with microwave irradiation. J Histochem Cytochem 2001; 49: 1099-109.

Bonucci E, Mocetti P, Silverstrini G, Ballanti P, Zalzal S, Fortin M, Nanci A. The osteoblastic phenotype in calcium-depleted and calcium-repleted rats: A structural and histomorphometric study. J Electron Microsc 2001; 50: 333-47.

Kawaguchi H, Ogawa T, Kurihara H, Nanci A. Immunodetection of noncollagenous matrix proteins during periodontal tissue regeneration. J Periodont Res 2001; 36: 205-13.

Orsini G, Zalzal S, Nanci A. Localized infusion of tunicamycin in rat hemimandibles: alteration of the basal lamina associated with maturation stage ameloblasts. J Histochem Cytochem 2001; 49: 165-76.

Orsini G, Lavoie P, Smith CE, Nanci A. Immunochemical characterization of a chicken egg yolk antibody to secretory forms of rat incisor amelogenin. J Histochem Cytochem 2001; 49: 285-92.

Brunski JB, Puleo DA, Nanci A. Biomaterials and biomechanics of oral and maxillofacial implants: current status and future developments. Int J Oral Maxillofac Implants 2000; 15: 15-46.

Mocetti P, Ballanti P, Zalzal S, Silvestrini G, Bonucci E, Nanci A. A histomorphometric, structural, and immunocytochemical study of the effects of diet-induced hypocalcemia on bone in growing rats. J Histochem Cytochem 2000; 48: 1059-77.

Nanci A, Mocetti P, Sakamoto Y, Kunikata M, Lozupone E, Bonucci E. Morphological and immunocytochemical analyses on the effects of diet-induced hypocalcemia on enamel maturation in the rat incisor. J Histochem Cytochem 2000; 48: 1043-57.

Nguyen TN, Wang HJ, Zalzal S, Nanci A, Nabi IR. Purification and characterization of beta-actin-rich tumor cell pseudopodia: role of glycolysis. Exp Cell Res 2000; 258: 171-83.

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